Safety without compromise

InteguPly is human acellular dermis (ACD) processed to maintain the biologic and structural integrity of the tissue’s extracellular matrix components, while delivering a Sterility Assurance Level (SAL) of 10-6.

Strong, biocompatible ACD

Wound Care and Reconstruction

Supports the repair or replacement of integumental tissue, as well as closure of chronic diabetic foot ulcers, venous leg ulcers and pressure wounds.

Sports Medicine

Support, protection, reinforcement or covering of tendon, ligament and rotator cuff

Robust Remodeling

InteguPly plays a key role at every step of the remodeling process. Implantation of InteguPly in vivo in a rabbit model shows active tissue regeneration. Deep infiltration of inflammatory cells (white arrows) precedes neovascularization (black arrows) consistent with healthy remodeling processes.2

InteguPly Quick Facts

  • Intact extracellular matrix that promotes tissue remodeling
  • Superior safety profile – over 20,000 applications with no adverse reactions reported
  • Rehydration in 37°C saline in approximately 10-20 minutes, depending on thickness

  • Acellular dermal matrix
  • Meshed acellular dermal matrix
  • Chronic wound healing
  • Reconstructive surgery


A wide variety of product sizes are available for InteguPly to meet the unique needs of your practice.  Please contact Aziyo for additional product details.



  1. LT-0003 Safety, Structure and Function of InteguPly.
  2. LT-0002 In vivo study of InteguPly. Results from laboratory testing or animal studies may not be predictive of clinical experience. Physicians and operating room personnel should review the package insert for product information, including indications, contraindications, precautions and warnings.
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