CorMatrix® ECM® for Pericardial Closure

CorMatrix® ECM® for Pericardial Closure enables surgeons to re-establish the essential native anatomic structure of the pericardium.

CorMatrix® ECM® for Pericardial Closure is used to restore the pericardium by providing a natural bioscaffold that allows the patient’s own cells to form a new pericardial layer.1 Absence of the pericardial barrier often leads to scarring and the formation of adhesions between the heart and sternum, impairing normal heart function.1,2 Reconstructing the pericardium facilitates less bleeding and re-exploration, safer re-entry, and may shorten operative times for redo. Reformation of the pericardium using CorMatrix® enables surgeons to re-establish this essential native anatomic structure.1


  • CorMatrix® remodels over time to restore healthy, pericardial tissue
  • Preserves the distance between the heart and sternum3
  • May shorten operative times for redo procedures
  • Enables accurate identification of post-operative bleeding4
  • Lacks the pro-inflammatory components of chemically fixed xenografts5
  • May improve hemodynamics by restoring normal anatomy6

Ordering Information

Product Number Size Thickness
CMCV-003-401 7cm x 10cm 4-PLY
CMCV-003-402 7cm x 15cm 4-PLY

CorMatrix® ECM® for Cardiac Tissue Repair

CorMatrix® ECM® is our next generation tool for repair of intracardiac structures. The ability to regrow and remodel makes it superior to inert patches that ultimately promote inflammation and scarring

CorMatrix® ECM® for Cardiac Tissue Repair is used to repair intracardiac tissues, damaged cardiac structures, or during procedures when cardiovascular prosthetics (such as valves) do not fit properly. CorMatrix® is ideal for intracardiac surgery based on its ability to structurally support repairs and remodel tissue. In cases such as atrial septal defect repair, CorMatrix® Cardiac Tissue Repair can effectively close a hole and generate new, healthy tissue in lieu of using objects such as nitinol plugs or synthetic patches. CorMatrix® is gradually replaced by native tissues as it remodels.


  • Effectively closes holes and restores natural cardiac tissue
  • Ideal for intracardiac repairs or procedures when cardiovascular prosthetics do not fit properly
  • Unlike synthetic grafts, CorMatrix® encourages the body’s natural immune response
  • CorMatrix® allows capillary in-growth and infiltration of white blood cells into newly remodeled tissue

Ideal Uses for CorMatrix®:

  • ASD Repair
  • VSD Repair
  • Aortic Root Enlargement
  • Left Ventricular Aneurysm Repair
  • Sinus of Valsalva Aneurysm
  • Repair of Cardiac Tumors
  • Endocarditis
  • Use as a Pledget
  • Suture Line Buttressing

Ordering Information

Product Number Size Thickness
CMCV-004-401 7cm x 10cm 4-PLY
CMCV-004-404 4cm x 7cm 4-PLY


Tyke® is the only ECM specifically cleared for use in neonates and infants.

Tyke® was developed from a request by Pediatric Cardiovascular Surgeons to deliver an ECM material that maintained the biomechanical properties found in our existing products, but was thinner, more pliable and better suited for intracardiac and branch pulmonary artery use in neonates and infants.

Tyke® is intended for use in neonates and infants for repair of pericardial structures, as an epicardial covering for damaged or repaired cardiac structures, as a patch material for intracardiac defects, septal defect and annulus repair, suture-line buttressing, and cardiac repair. Tyke® meets the same biomechanical requirements (tensile strength, suture retention strength and burst strength) as our existing CorMatrix® ECM® for Cardiac Tissue Repair and bench testing has shown that Tyke® exceeds the specified tensile strength, suture retention strength, and burst strength required for its intended surgical use.

To assess the biological performance of Tyke®, patches were implanted in the descending aorta and pulmonary artery of a growing lamb model. Explanted patches were evaluated by an independent, board-certified pathologist. Tyke® was found to restore the structural integrity (including the formation of a mature, stable, and fully endothelialized neointima) of the implant site within 90 days (Figure 1). By 180 days, the thickness of the remodeled Tyke® patch was similar to the thickness of the adjacent native artery.

Ordering Information

Product Number Size Thickness
CMCV-099-204 4cm x 7cm 2-PLY

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